Development, Maturation, and Function of Cortical Circuits

Currently we are working on projects that investigate:

1) The role of a transcriptional regulator in differentiation of neurons and glia in the cortex, and its potential impact in autism and intellectual disability

Distinct molecular markers in diverse cortical neurons subtypes

2) Regulation of neuron-specific characteristics via miRNAs

In-utero electroporation to study the regulation of neuronal properties

3) The mechanisms of neuron identity plasticity and maintenance during maturation of cortical output circuits

Viral tracers manipulation to characterize the cortical circuits and function

4) Role of normal and altered cortico-thalamic circuit activity in working memory

Studying the cortico-thalamic circuits using transgenic Syt6Cre mouse model